Concentration- and schedule-dependent effects of chemotherapy on the angiogenic potential and drug sensitivity of vascular endothelial cells

The anti-angiogenic activity of chemotherapy is both dose- and schedule-dependent. While conventional maximum tolerated dose (MTD) chemotherapy exerts only mild and reversible anti-angiogenic effects, low-dose metronomic (LDM) chemotherapy was developed to specifically target tumour angiogenesis. Ho...

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Detalhes bibliográficos
Main Authors: Pasquier, Eddy, Tuset, Maria-Pia, Street, Janine, Sinnappan, Snega, MacKenzie, Karen L., Braguer, Diane, Andre, Nicolas, Kavallaris, Maria
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2012
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Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3595478/
https://ncbi.nlm.nih.gov/pubmed/23143659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10456-012-9321-x
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