BCL-2 inhibition targets oxidative phosphorylation and selectively eradicates quiescent human leukemia stem cells

Most forms of chemotherapy employ mechanisms involving induction of oxidative stress, a strategy that can be effective due to the elevated oxidative state commonly observed in cancer cells. However, recent studies have shown that relative redox levels in primary tumors can be heterogeneous, suggesti...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Glavni autori: Lagadinou, Eleni D., Sach, Alexander, Callahan, Kevin, Rossi, Randall M., Neering, Sarah J., Minhajuddin, Mohammad, Ashton, John M., Pei, Shanshan, Grose, Valerie, O’Dwyer, Kristen M., Liesveld, Jane L., Brookes, Paul S., Becker, Michael W., Jordan, Craig T.
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3595363/
https://ncbi.nlm.nih.gov/pubmed/23333149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2012.12.013
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items