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A functional trinucleotide repeat polymorphism in the 5’-untranslated region of the glutathione biosynthetic gene GCLC is associated with increased risk for lung and aerodigestive tract cancers

Glutathione (GSH), the major intracellular antioxidant, protects against cancer development by detoxifying carcinogens and free radicals and strengthening the immune system. Recently, a GAG-trinucleotide repeat polymorphism in the 5’-untraslated region of the gene for the rate limiting enzyme for GS...

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Detalhes bibliográficos
Main Authors: Nichenametla, Sailendra N, Muscat, Joshua E, Liao, Jason G, Lazarus, Philip, Richie, John P
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3595361/
https://ncbi.nlm.nih.gov/pubmed/22610501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.21923
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