Cargando...

HnRNP L and HnRNP A1 Induce Extended U1 snRNA Interactions with an Exon to Repress Spliceosome Assembly

Pre-mRNA splicing is catalyzed through the activity of the spliceosome, a dynamic enzymatic complex. Forcing aberrant interactions within the spliceosome can reduce splicing efficiency and alter splice site choice; however, it is unknown whether such alterations are naturally exploited mechanisms of...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Chiou, Ni-ting, Shankarling, Ganesh, Lynch, Kristen W.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3595347/
https://ncbi.nlm.nih.gov/pubmed/23394998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2012.12.025
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!