CovR and VicRK Regulate Cell Surface Biogenesis Genes Required for Biofilm Formation in Streptococcus mutans

The two-component system VicRK and the orphan regulator CovR of Streptococcus mutans co-regulate a group of virulence genes associated with the synthesis of and interaction with extracellular polysaccharides of the biofilm matrix. Knockout mutants of vicK and covR display abnormal cell division and...

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Bibliographic Details
Main Authors: Stipp, Rafael N., Boisvert, Heike, Smith, Daniel J., Höfling, José F., Duncan, Margaret J., Mattos-Graner, Renata O.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3595261/
https://ncbi.nlm.nih.gov/pubmed/23554881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0058271
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