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Assigning Quantitative Function to Post-Translational Modifications Reveals Multiple Sites of Phosphorylation That Tune Yeast Pheromone Signaling Output

Cell signaling systems transmit information by post-translationally modifying signaling proteins, often via phosphorylation. While thousands of sites of phosphorylation have been identified in proteomic studies, the vast majority of sites have no known function. Assigning functional roles to the cat...

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Hlavní autoři: Pincus, David, Ryan, Christopher J., Smith, Richard D., Brent, Roger, Resnekov, Orna
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3595240/
https://ncbi.nlm.nih.gov/pubmed/23554854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056544
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