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Abdominal obesity, independently from caloric intake, accounts for the development of intestinal tumors in Apc(1638N/+) female mice

To determine whether visceral fat (VF), independent of other confounders, is causally linked to intestinal tumorigenesis, we surgically removed VF in Apc(1638/N+) mice. At 15 wks of age, male and female Apc(1638/N+) mice were randomized to one of three groups: sham operated (AL), VF removal (VF-), o...

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Detalhes bibliográficos
Main Authors: Huffman, Derek M., Augenlicht, Leonard H., Zhang, Xueying, Lofrese, John J., Atzmon, Gil, Chamberland, John P., Mantzoros, Christos S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3595118/
https://ncbi.nlm.nih.gov/pubmed/23466815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-12-0414
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