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Impaired selection of IgA and intestinal dysbiosis associated with PD-1-deficiency

A major function of immunoglobulin A (IgA) is to maintain balanced bacterial communities in the gut. We have previously shown that diversification of IgA upon somatic hypermutation (SHM) is critical for IgA function yet the principles governing the selection of IgA in the gut have remained elusive....

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書誌詳細
主要な著者: Maruya, Mikako, Kawamoto, Shimpei, Kato, Lucia M., Fagarasan, Sidonia
フォーマット: Artigo
言語:Inglês
出版事項: Landes Bioscience 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3595078/
https://ncbi.nlm.nih.gov/pubmed/23333864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/gmic.23595
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