Near-zero linking difference upon transcription factor IID binding to promoter DNA.

Binding of yeast transcription factor IID (TFIID) to the adenoviral major late promoter in circular DNA molecules caused a linking number change of less than 0.1. TFIID on its own therefore fails to unwind DNA appreciably, or else it causes both unwinding and compensatory writhing. Highly purified,...

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Bibliographic Details
Published in:Mol Cell Biol
Main Authors: Lorch, Y, Kornberg, R D
Format: Artigo
Language:Inglês
Published: Taylor & Francis 1993
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359500/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8382777/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.3.1872
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