The pharmacokinetics and safety of an intraoperative bupivacaine-collagen implant (XaraColl(®)) for postoperative analgesia in women following total abdominal hysterectomy

BACKGROUND: XaraColl(®), a collagen-based intraoperative implant that delivers bupivacaine to the site of surgical trauma, is under development for postoperative analgesia. We examined the pharmacokinetics, safety and efficacy of XaraColl following implantation in women undergoing total abdominal hy...

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Autors principals: Cusack, Susan L, Reginald, Philip, Hemsen, Lisa, Umerah, Emmanuel
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2013
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3594918/
https://ncbi.nlm.nih.gov/pubmed/23503706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/JPR.S40976
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