Loss of β-Catenin Induces Multifocal Periosteal Chondroma-Like Masses in Mice

Osteochondromas and enchondromas are the most common tumors affecting the skeleton. Osteochondromas can occur as multiple lesions, such as those in patients with hereditary multiple exostoses. Unexpectedly, while studying the role of β-catenin in cartilage development, we found that its conditional...

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Detalhes bibliográficos
Main Authors: Cantley, Leslie, Saunders, Cheri, Guttenberg, Marta, Candela, Maria Elena, Ohta, Yoichi, Yasuhara, Rika, Kondo, Naoki, Sgariglia, Federica, Asai, Shuji, Zhang, Xianrong, Qin, Ling, Hecht, Jacqueline T., Chen, Di, Yamamoto, Masato, Toyosawa, Satoru, Dormans, John P., Esko, Jeffrey D., Yamaguchi, Yu, Iwamoto, Masahiro, Pacifici, Maurizio, Enomoto-Iwamoto, Motomi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2013
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3594871/
https://ncbi.nlm.nih.gov/pubmed/23274133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2012.11.012
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