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A tightly associated serine/threonine protein kinase regulates phosphoinositide 3-kinase activity.

We identified a serine/threonine protein kinase that is associated with and phosphorylates phosphoinositide 3-kinase (PtdIns 3-kinase). The serine kinase phosphorylates both the 85- and 110-kDa subunits of PtdIns 3-kinase and purifies with it from rat liver and immunoprecipitates with antibodies rai...

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Detalhes bibliográficos
Main Authors: Carpenter, C L, Auger, K R, Duckworth, B C, Hou, W M, Schaffhausen, B, Cantley, L C
Formato: Artigo
Idioma:Inglês
Publicado em: 1993
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC359478/
https://ncbi.nlm.nih.gov/pubmed/8382773
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