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p53-mediated cell death: relationship to cell cycle control.

M1 clone S6 myeloid leukemic cells do not express detectable p53 protein. When stably transfected with a temperature-sensitive mutant of p53, these cells undergo rapid cell death upon induction of wild-type (wt) p53 activity at the permissive temperature. This process has features of apoptosis. In a...

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Auteurs principaux: Yonish-Rouach, E, Grunwald, D, Wilder, S, Kimchi, A, May, E, Lawrence, J J, May, P, Oren, M
Format: Artigo
Langue:Inglês
Publié: 1993
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC359451/
https://ncbi.nlm.nih.gov/pubmed/8441387
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