Fluorinated N, N’-Diarylureas as AMPK Activators

Adenosine monophosphate-activated kinase (AMPK) plays a central role in regulating energy homeostasis in eukaryotic cells. AMPK also regulates lipid synthesis by inhibiting acetyl-CoA carboxylase (ACC) and regulates mTOR signaling by activating TSC2. Due to its important roles in cell metabolism, AM...

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Detalhes bibliográficos
Main Authors: Sviripa, Vitaliy, Zhang, Wen, Conroy, Michael D., Schmidt, Eric S., Liu, Alice X., Truong, Johnny, Liu, Chunming, Watt, David S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3594501/
https://ncbi.nlm.nih.gov/pubmed/23414799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2013.01.096
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