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Bioinformatics of varicella-zoster virus: Single nucleotide polymorphisms define clades and attenuated vaccine genotypes

Varicella zoster virus (VZV) is one of the human herpesviruses. To date, over 40 complete VZV genomes have been sequenced and analyzed. The VZV genome contains around 125,000 base pairs including 70 open reading frames (ORFs). Enumeration of single nucleotide polymorphisms (SNPs) has determined that...

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Autors principals: Chow, Vincent T., Tipples, Graham A., Grose, Charles
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3594394/
https://ncbi.nlm.nih.gov/pubmed/23183312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.meegid.2012.11.008
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