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Calcium entry via TRPC1 channels activates chloride currents in human glioma cells

Malignant gliomas are highly-invasive brain cancers that carry a dismal prognosis. Recent studies indicate that Cl(−) channels facilitate glioma cell invasion by promoting hydrodynamic cell shape and volume changes. Here we asked how Cl(−) channels are regulated in the context of migration. Using pa...

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Detalhes bibliográficos
Main Authors: Cuddapah, Vishnu Anand, Turner, Kathryn L., Sontheimer, Harald
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3594368/
https://ncbi.nlm.nih.gov/pubmed/23261316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceca.2012.11.013
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