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Males, but not females, lose tyrosine hydroxylase fibers in the medial prefrontal cortex and are impaired on a delayed alternation task during aging

The structure of the prefrontal cortex (PFC) is particularly vulnerable to the effects of aging, and behaviors mediated by the PFC are impaired during aging in both humans and animals. In male rats, behavioral deficits have been correlated with a decrease in dopaminergic functioning. However, studie...

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Autores principales: Chisholm, Nioka C., Kim, Taehyeon, Juraska, Janice M.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3594341/
https://ncbi.nlm.nih.gov/pubmed/23327742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbr.2013.01.009
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