Evaluation of the Lymphocyte Trafficking Drug FTY720 in Vaginal Tissues

BACKGROUND: FTY720 is an immunomodulatory agent that reduces lymphocytes in peripheral tissues and circulation. Such agents may be effective as vaginal microbicides for HIV prevention. Systemic or vaginal application of FTY720 may reduce lymphocyte concentrations in genital tissues, reducing HIV tar...

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Main Authors: Tsuiki, Ai, Luo, Wei, Henning, Tara, Vishwanathan, Sundaram, Dinh, Chuong, Adams, Debra, Sweeney, Elizabeth, Mitchell, James, Bachman, Shannon, Sharma, Prachi, Powell, Nathaniel, Hendry, R. Michael, McNicholl, Janet, Kersh, Ellen
格式: Artigo
語言:Inglês
出版: 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3594332/
https://ncbi.nlm.nih.gov/pubmed/23311598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jmp.12033
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