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Promoter hijack reveals pericentrin functions in mitosis and the DNA damage response

Centrosomes, the principal microtubule-organizing centers of animal somatic cells, consist of two centrioles embedded in the pericentriolar material (PCM). Pericentrin is a large PCM protein that is required for normal PCM assembly. Mutations in PCNT cause primordial dwarfism. Pericentrin has also b...

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Detalhes bibliográficos
Main Authors: Wang, Yifan, Dantas, Tiago J., Lalor, Pierce, Dockery, Peter, Morrison, Ciaran G.
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3594264/
https://ncbi.nlm.nih.gov/pubmed/23324397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.23516
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