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Elaborate security TRAINing to fight against expression of genomic junk

A new study shows that the expression of two classes of repetitive elements in the mouse genome is controlled through two complementary mechanisms: DNA methylation and p53-mediated transcription suppression.¹ When both lines of defense fail, expression of the repeats yields large quantities of doubl...

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Hlavní autor: Koonin, Eugene V.
Médium: Artigo
Jazyk:Inglês
Vydáno: Landes Bioscience 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3594256/
https://ncbi.nlm.nih.gov/pubmed/23370394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.23717
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