Prevalence of BRCA1 Mutations in Familial and Sporadic Greek Ovarian Cancer Cases

Germline mutations in the BRCA1 and BRCA2 genes contribute to approximately 18% of hereditary ovarian cancers conferring an estimated lifetime risk from 15% to 50%. A variable incidence of mutations has been reported for these genes in ovarian cancer cases from different populations. In Greece, six...

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Bibliografische gegevens
Hoofdauteurs: Stavropoulou, Alexandra V., Fostira, Florentia, Pertesi, Maroulio, Tsitlaidou, Marianthi, Voutsinas, Gerassimos E., Triantafyllidou, Olga, Bamias, Aristotelis, Dimopoulos, Meletios A., Timotheadou, Eleni, Pectasides, Dimitrios, Christodoulou, Christos, Klouvas, George, Papadimitriou, Christos, Makatsoris, Thomas, Pentheroudakis, George, Aravantinos, Gerasimos, Karydakis, Vassilis, Yannoukakos, Drakoulis, Fountzilas, George, Konstantopoulou, Irene
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2013
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3594241/
https://ncbi.nlm.nih.gov/pubmed/23536787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0058182
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