Prevalence of BRCA1 Mutations in Familial and Sporadic Greek Ovarian Cancer Cases

Germline mutations in the BRCA1 and BRCA2 genes contribute to approximately 18% of hereditary ovarian cancers conferring an estimated lifetime risk from 15% to 50%. A variable incidence of mutations has been reported for these genes in ovarian cancer cases from different populations. In Greece, six...

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Main Authors: Stavropoulou, Alexandra V., Fostira, Florentia, Pertesi, Maroulio, Tsitlaidou, Marianthi, Voutsinas, Gerassimos E., Triantafyllidou, Olga, Bamias, Aristotelis, Dimopoulos, Meletios A., Timotheadou, Eleni, Pectasides, Dimitrios, Christodoulou, Christos, Klouvas, George, Papadimitriou, Christos, Makatsoris, Thomas, Pentheroudakis, George, Aravantinos, Gerasimos, Karydakis, Vassilis, Yannoukakos, Drakoulis, Fountzilas, George, Konstantopoulou, Irene
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3594241/
https://ncbi.nlm.nih.gov/pubmed/23536787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0058182
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