CD44 interacts with EGFR and Promotes Head and Neck Squamous Cell Carcinoma Initiation and Progression

OBJECTIVES: CD44 is a promising target for therapy in Head and Neck Squamous Cell carcinoma (HNSCC) and has two defined roles in tumorigenesis: it is a cancer stem cell (CSC) marker and it promotes migration and proliferation through interaction with many signaling molecules. The purpose of this stu...

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Bibliographische Detailangaben
Hauptverfasser: Perez, Aymee, Neskey, David M., Wen, Judy, Pereira, Lutecia, Reategui, Erika P., Goodwin, W. Jarrard, Carraway, Kermit L., Franzmann, Elizabeth J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3594090/
https://ncbi.nlm.nih.gov/pubmed/23265944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.oraloncology.2012.11.009
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