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Porphyrin-Substituted H-NOX Proteins as High Relaxivity MRI Contrast Agents

Heme proteins are exquisitely tuned to carry out diverse biological functions while employing the identical heme cofactor. Although heme protein properties are often altered through modification of the protein scaffold, protein function can be greatly expanded and diversified through replacement of...

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Autors principals: Winter, Michael B., Klemm, Piper J., Phillips-Piro, Christine M., Raymond, Kenneth N., Marletta, Michael A.
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3594055/
https://ncbi.nlm.nih.gov/pubmed/23394479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ic302685h
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