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Profile of bosutinib and its clinical potential in the treatment of chronic myeloid leukemia
Bosutinib (SKI-606) is an orally available, once-daily, dual Src and Abl kinase inhibitor with promising clinical potential in first-, second-, and third-line treatment of chronic myeloid leukemia (CML). Bosutinib effectively inhibits wild-type BCR-ABL and most imatinib-resistant BCR-ABL mutations e...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Dove Medical Press
2013
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3594007/ https://ncbi.nlm.nih.gov/pubmed/23493838 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S19901 |
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