Dual roles of Sema6D in cardiac morphogenesis through region-specific association of its receptor, Plexin-A1, with off-track and vascular endothelial growth factor receptor type 2

Semaphorins, originally identified as axon guidance factors in the nervous system, play integral roles in organogenesis. Here, we demonstrate a critical involvement of Sema6D in cardiac morphogenesis. Ectopic expression of Sema6D or RNA interference against Sema6D induces expansion or narrowing of t...

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Detalhes bibliográficos
Main Authors: Toyofuku, Toshihiko, Zhang, Hong, Kumanogoh, Atsushi, Takegahara, Noriko, Suto, Fumikazu, Kamei, Junko, Aoki, Kazuhiro, Yabuki, Masanori, Hori, Masatsugu, Fujisawa, Hajime, Kikutani, Hitoshi
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2004
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC359397/
https://ncbi.nlm.nih.gov/pubmed/14977921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1167304
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