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Role of the TAK1-NLK-STAT3 pathway in TGF-β-mediated mesoderm induction

Transforming growth factor (TGF)-β-activated kinase 1 (TAK1) and Nemo-like kinase (NLK) function in Xenopus, Drosophila, and Caenorhabditis elegans development. Here we report that serine phosphorylation of STAT3 induced by TAK1-NLK cascade is essential for TGF-β-mediated mesoderm induction in Xenop...

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Pubblicato in:Genes Dev
Autori principali: Ohkawara, Bisei, Shirakabe, Kyoko, Hyodo-Miura, Junko, Matsuo, Ritsuko, Ueno, Naoto, Matsumoto, Kunihiro, Shibuya, Hiroshi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2004
Soggetti:
Research Communications
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359392/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15004007/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.1166904
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