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Unraveling the signaling pathways promoting fibrosis in Dupuytren's disease reveals TNF as a therapeutic target

Dupuytren's disease is a very common progressive fibrosis of the palm leading to flexion deformities of the digits that impair hand function. The cell responsible for development of the disease is the myofibroblast. There is currently no treatment for early disease or for preventing recurrence...

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מידע ביבליוגרפי
Main Authors: Verjee, Liaquat S., Verhoekx, Jennifer S. N., Chan, James K. K., Krausgruber, Thomas, Nicolaidou, Vicky, Izadi, David, Davidson, Dominique, Feldmann, Marc, Midwood, Kim S., Nanchahal, Jagdeep
פורמט: Artigo
שפה:Inglês
יצא לאור: National Academy of Sciences 2013
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3593900/
https://ncbi.nlm.nih.gov/pubmed/23431165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1301100110
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