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Spatial mismatch between the Na(+) flux and spike initiation in axon initial segment

It is widely believed that, in cortical pyramidal cells, action potentials (APs) initiate in the distal portion of axon initial segment (AIS) because that is where Na(+) channel density is highest. To investigate the relationship between the density of Na(+) channels and the spatiotemporal pattern o...

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Autors principals: Baranauskas, Gytis, David, Yaron, Fleidervish, Ilya A.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3593864/
https://ncbi.nlm.nih.gov/pubmed/23341597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1215125110
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