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Nascent peptides that block protein synthesis in bacteria

Although the ribosome is a very general catalyst, it cannot synthesize all protein sequences equally well. For example, ribosomes stall on the secretion monitor (SecM) leader peptide to regulate expression of a downstream gene. Using a genetic selection in Escherichia coli, we identified additional...

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Bibliografische gegevens
Hoofdauteurs: Woolstenhulme, Christopher J., Parajuli, Shankar, Healey, David W., Valverde, Diana P., Petersen, E. Nicholas, Starosta, Agata L., Guydosh, Nicholas R., Johnson, W. Evan, Wilson, Daniel N., Buskirk, Allen R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3593848/
https://ncbi.nlm.nih.gov/pubmed/23431150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1219536110
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