Characterization of cellular uptake and toxicity of aminosilane-coated iron oxide nanoparticles with different charges in central nervous system-relevant cell culture models

BACKGROUND: Aminosilane-coated iron oxide nanoparticles (AmS-IONPs) have been widely used in constructing complex and multifunctional drug delivery systems. However, the biocompatibility and uptake characteristics of AmS-IONPs in central nervous system (CNS)-relevant cells are unknown. The purpose o...

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Autori principali: Sun, Zhizhi, Yathindranath, Vinith, Worden, Matthew, Thliveris, James A, Chu, Stephanie, Parkinson, Fiona E, Hegmann, Torsten, Miller, Donald W
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove Medical Press 2013
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Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3593762/
https://ncbi.nlm.nih.gov/pubmed/23494517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S39048
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