Extracellular Matrix Remodeling: The Common Denominator in Connective Tissue Diseases Possibilities for Evaluation and Current Understanding of the Matrix as More Than a Passive Architecture, but a Key Player in Tissue Failure

Increased attention is paid to the structural components of tissues. These components are mostly collagens and various proteoglycans. Emerging evidence suggests that altered components and noncoded modifications of the matrix may be both initiators and drivers of disease, exemplified by excessive ti...

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Autores principales: Karsdal, Morten A., Nielsen, Mette J., Sand, Jannie M., Henriksen, Kim, Genovese, Federica, Bay-Jensen, Anne-Christine, Smith, Victoria, Adamkewicz, Joanne I., Christiansen, Claus, Leeming, Diana J.
Formato: Artigo
Lenguaje:Inglês
Publicado: Mary Ann Liebert, Inc. 2013
Materias:
Review Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3593693/
https://ncbi.nlm.nih.gov/pubmed/23046407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/adt.2012.474
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