The expression of Axl receptor tyrosine kinase influences the tumour phenotype and clinical outcome of patients with malignant pleural mesothelioma

BACKGROUND: Recent preclinical studies identified Axl, a tyrosine kinase receptor implicated in tumour progression and epithelial-to-mesenchymal transition, as a putative therapeutic target in malignant pleural mesothelioma (MPM), an invariably fatal malignancy with limited treatment options. Here,...

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Main Authors: Pinato, D J, Mauri, F A, Lloyd, T, Vaira, V, Casadio, C, Boldorini, R L, Sharma, R
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2013
Fag:
Molecular Diagnostics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3593571/
https://ncbi.nlm.nih.gov/pubmed/23361052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2013.9
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