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Cancer heterogeneity: implications for targeted therapeutics

Developments in genomic techniques have provided insight into the remarkable genetic complexity of malignant tumours. There is increasing evidence that solid tumours may comprise of subpopulations of cells with distinct genomic alterations within the same tumour, a phenomenon termed intra-tumour het...

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Detalhes bibliográficos
Main Authors: Fisher, R, Pusztai, L, Swanton, C
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3593543/
https://ncbi.nlm.nih.gov/pubmed/23299535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2012.581
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