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How antipsychotics work—From receptors to reality

How does a small molecule blocking a few receptors change a patients’ passionately held paranoid belief that the FBI is out to get him? To address this central puzzle of anti-psychotic action, we review a framework linking dopamine neurochemistry to psychosis, and then link this framework to the mec...

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Bibliografiske detaljer
Main Authors: Kapur, Shitij, Agid, Ofer, Mizrahi, Romina, Li, Ming
Format: Artigo
Sprog:Inglês
Udgivet: Springer-Verlag 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3593357/
https://ncbi.nlm.nih.gov/pubmed/16490410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nurx.2005.12.003
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