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Pathophysiological mechanisms in antiphospholipid syndrome

Antiphospholipid syndrome is a systemic autoimmune disease associated with thrombosis and recurrent fetal loss in the setting of detectable antiphospholipid (aPL) antibodies. The major antigenic target has been identifed as β(2)-glycoprotein I (β(2)GPI), which mediates binding of aPL antibodies to t...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Harper, Brock E, Wills, Rohan, Pierangeli, Silvia S
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3593246/
https://ncbi.nlm.nih.gov/pubmed/23487578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/ijr.11.9
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