Apurinic/apyrimidinic endonuclease-1 (APE-1) is overexpressed via the activation of NF-κB-p65 in MCP-1-positive esophageal squamous cell carcinoma tissue

Apurinic/apyrimidinic endonuclease-1 (APE-1), a key enzyme responsible for DNA base excision repair (BER), has been linked to cancer chemoradiosensitivity. The phosphorylation of p65 plays a role in the activation of this pathway. In this study, we investigated APE-1 expression and its interaction w...

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Detalhes bibliográficos
Main Authors: Song, Junmin, Futagami, Seiji, Nagoya, Hiroyuki, Kawagoe, Tetsuro, Yamawaki, Hiroshi, Kodaka, Yasuhiro, Tatsuguchi, Atsushi, Gudis, Katya, Wakabayashi, Taiga, Yonezawa, Masaoki, Shimpuku, Mayumi, Watarai, Yasuhiko, Iwakiri, Katsuhiko, Hoshihara, Yoshio, Makino, Hiroshi, Miyashita, Masao, Tsuchiya, Shinichi, Li, Yan, E. Crowe, Sheila, Sakamoto, Choitsu
Formato: Artigo
Idioma:Inglês
Publicado em: the Society for Free Radical Research Japan 2013
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3593127/
https://ncbi.nlm.nih.gov/pubmed/23525727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3164/jcbn.12-95
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