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The basic helix-loop-helix-zipper domain of TFE3 mediates enhancer-promoter interaction.

Binding sites for three families of sequence-specific DNA-binding proteins, microE3, C/EBP, and OCT, are found in both the promoters and the intronic enhancer of the immunoglobulin heavy-chain gene. We have used a cotransfection system to investigate how proteins binding these sites may participate...

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Autors principals: Artandi, S E, Cooper, C, Shrivastava, A, Calame, K
Format: Artigo
Idioma:Inglês
Publicat: 1994
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC359312/
https://ncbi.nlm.nih.gov/pubmed/7969114
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