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Blockade of Autocrine TGF-β Signaling Inhibits Stem Cell Phenotype, Survival, and Metastasis of Murine Breast Cancer Cells

Transforming growth factor beta (TGF-β) signaling has been implicated in driving tumor progression and metastasis by inducing stem cell-like features in some human cancer cell lines. In this study, we have utilized a novel murine cell line NMuMG-ST, which acquired cancer stem cell (CSC) phenotypes d...

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Main Authors: Liu, Zhao, Bandyopadhyay, Abhik, Nichols, Robert W., Wang, Long, Hinck, Andrew P., Wang, Shui, Sun, Lu-Zhe
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3593047/
https://ncbi.nlm.nih.gov/pubmed/23482850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4172/2157-7633.1000116
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