Combined Chelation Therapy with Deferasirox and Deferoxamine in Thalassemia

Iron overload is the primary cause of mortality and morbidity in thalassemia major despite advances in chelation therapy. We performed a pilot clinical trial to evaluate the safety and efficacy of combined therapy with deferasirox (DFX, 20-30 mg/kg daily) and deferoxamine (DFO, 35-50 mg/kg on 3-7 da...

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Autori principali: Lal, Ashutosh, Porter, John, Sweeters, Nancy, Ng, Vivian, Evans, Patricia, Neumayr, Lynne, Kurio, Gregory, Harmatz, Paul, Vichinsky, Elliott
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3592978/
https://ncbi.nlm.nih.gov/pubmed/23151373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcmd.2012.10.006
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