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Mechanistic insights into the impairment of memory B cells and antibody production in the elderly

It is well established that immunologic memory generated early in life can be maintained into old age and mediate robust anamnestic antibody responses. Little is known, however, about the initiation of memory B cells in the elderly. We have conducted a prospective analysis of the quantities and func...

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Detalhes bibliográficos
Main Authors: Aberle, Judith H., Stiasny, Karin, Kundi, Michael, Heinz, Franz X.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3592966/
https://ncbi.nlm.nih.gov/pubmed/22282053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-011-9371-9
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