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Effects of Metformin on Burn-Induced Hepatic Endoplasmic Reticulum Stress in Male Rats

Severe burn injury causes hepatic dysfunction that results in major metabolic derangements including insulin resistance and hyperglycemia and is associated with hepatic endoplasmic reticulum (ER) stress. We have recently shown that insulin reduces ER stress and improves liver function and morphology...

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Hlavní autoři: Hiyama, Yaeko, Marshall, Alexandra H, Kraft, Robert, Qa’aty, Nour, Arno, Anna, Herndon, David N, Jeschke, Marc G
Médium: Artigo
Jazyk:Inglês
Vydáno: ScholarOne 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3592932/
https://ncbi.nlm.nih.gov/pubmed/23348514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2012.00330
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