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Effects of Metformin on Burn-Induced Hepatic Endoplasmic Reticulum Stress in Male Rats

Severe burn injury causes hepatic dysfunction that results in major metabolic derangements including insulin resistance and hyperglycemia and is associated with hepatic endoplasmic reticulum (ER) stress. We have recently shown that insulin reduces ER stress and improves liver function and morphology...

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Autores principales: Hiyama, Yaeko, Marshall, Alexandra H, Kraft, Robert, Qa’aty, Nour, Arno, Anna, Herndon, David N, Jeschke, Marc G
Formato: Artigo
Lenguaje:Inglês
Publicado: ScholarOne 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3592932/
https://ncbi.nlm.nih.gov/pubmed/23348514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2012.00330
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