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Antagonistic Pleiotropy at the Human IL6 Promoter Confers Genetic Resilience to the Pro-Inflammatory Effects of Adverse Social Conditions in Adolescence

The authors tested the evolutionary genetic hypothesis that the functional form of an asymmetrically risky Gene × Environment interaction will differ as a function of age-related antagonistic pleiotropy (i.e., show opposite effects in young vs. old individuals). Previous studies have identified a po...

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Detalhes bibliográficos
Main Authors: Cole, Steven W., Arevalo, Jesusa M. G., Manu, Kavya, Telzer, Eva H., Kiang, Lisa, Bower, Julienne E., Irwin, Michael R., Fuligni, Andrew J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3592928/
https://ncbi.nlm.nih.gov/pubmed/21639625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1037/a0023871
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