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Activation of the DNA-binding ability of human heat shock transcription factor 1 may involve the transition from an intramolecular to an intermolecular triple-stranded coiled-coil structure.

Heat stress regulation of human heat shock genes is mediated by human heat shock transcription factor hHSF1, which contains three 4-3 hydrophobic repeats (LZ1 to LZ3). In unstressed human cells (37 degrees C), hHSF1 appears to be in an inactive, monomeric state that may be maintained through intramo...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Cell Biol
Prif Awduron: Zuo, J, Baler, R, Dahl, G, Voellmy, R
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Taylor & Francis 1994
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359292/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7935471/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.14.11.7557-7568.1994
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