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Formation of Cystine Slipknots in Dimeric Proteins

We consider mechanical stability of dimeric and monomeric proteins with the cystine knot motif. A structure based dynamical model is used to demonstrate that all dimeric and some monomeric proteins of this kind should have considerable resistance to stretching that is significantly larger than that...

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Detalles Bibliográficos
Main Authors: Sikora, Mateusz, Cieplak, Marek
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2013
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3592873/
https://ncbi.nlm.nih.gov/pubmed/23520470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0057443
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