2,3,7,8-Tetrachlorodibenzo-p-Dioxin Promotes BHV-1 Infection in Mammalian Cells by Interfering with Iron Homeostasis Regulation

Mammalian cells require iron to satisfy metabolic needs or to accomplish specialized functions, and DNA viruses, like bovine herpesvirus 1 (BHV-1), require an iron-replete host to efficiently replicate, so that iron bioavailability is an important component of viral virulence. Cellular iron metaboli...

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Detalhes bibliográficos
Main Authors: Fiorito, Filomena, Irace, Carlo, Di Pascale, Antonio, Colonna, Alfredo, Iovane, Giuseppe, Pagnini, Ugo, Santamaria, Rita, De Martino, Luisa
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3592816/
https://ncbi.nlm.nih.gov/pubmed/23520538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0058845
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