Hypoxia Antagonizes Glucose Deprivation on Interleukin 6 Expression in an Akt Dependent, but HIF-1/2α Independent Manner

Although both glucose deprivation and hypoxia have been reported to promote cascades of biological alterations that lead to induction of inflammatory mediators, we hypothesized that glucose deprivation and hypoxia might show neutral, synergistic or antagonistic effects to each other on gene expressi...

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Bibliographic Details
Main Authors: Choi, Sung Ji, Shin, Ik Jae, Je, Kang-Hoon, Min, Eun Kyoung, Kim, Eun Ji, Kim, Hee-Sun, Choe, Senyon, Kim, Dong-Eog, Lee, Dong Kun
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3592797/
https://ncbi.nlm.nih.gov/pubmed/23520526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0058662
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