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Anisomycin-activated protein kinases p45 and p55 but not mitogen-activated protein kinases ERK-1 and -2 are implicated in the induction of c-fos and c-jun.

Independent of its ability to block translation, anisomycin intrinsically initiates intracellular signals and immediate-early gene induction [L. C. Mahadevan and D. R. Edwards, Nature (London) 349:747-749, 1991]. Here, we characterize further its action as a potent, selective signalling agonist. In-...

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Bibliografiske detaljer
Udgivet i:Mol Cell Biol
Main Authors: Cano, E, Hazzalin, C A, Mahadevan, L C
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 1994
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359270/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7935449/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.14.11.7352
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