Cell-Cycle-Dependent Structural Transitions in the Human CENP-A Nucleosome In Vivo

In eukaryotes, DNA is packaged into chromatin by canonical histone proteins. The specialized histone H3 variant CENP-A provides an epigenetic and structural basis for chromosome segregation by replacing H3 at centromeres. Unlike exclusively octameric canonical H3 nucleosomes, CENP-A nucleosomes have...

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Main Authors: Bui, Minh, Dimitriadis, Emilios K., Hoischen, Christian, An, Eunkyung, Quénet, Delphine, Giebe, Sindy, Nita-Lazar, Aleksandra, Diekmann, Stephan, Dalal, Yamini
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3592566/
https://ncbi.nlm.nih.gov/pubmed/22817894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.05.035
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