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Identification of one of the apurinic/apyrimidinic lyase active sites of topoisomerase V by structural and functional studies
Topoisomerase V (Topo-V) is the only member of a novel topoisomerase subtype. Topo-V is unique because it is a bifunctional enzyme carrying both topoisomerase and DNA repair lyase activities within the same protein. Previous studies had shown that the topoisomerase domain spans the N-terminus of the...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3592480/ https://ncbi.nlm.nih.gov/pubmed/23125368 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks1017 |
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