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Identification of one of the apurinic/apyrimidinic lyase active sites of topoisomerase V by structural and functional studies
Topoisomerase V (Topo-V) is the only member of a novel topoisomerase subtype. Topo-V is unique because it is a bifunctional enzyme carrying both topoisomerase and DNA repair lyase activities within the same protein. Previous studies had shown that the topoisomerase domain spans the N-terminus of the...
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| Hoofdauteurs: | , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Oxford University Press
2013
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3592480/ https://ncbi.nlm.nih.gov/pubmed/23125368 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks1017 |
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