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Structural asymmetry in the Thermus thermophilus RuvC dimer suggests a basis for sequential strand cleavages during Holliday junction resolution

Holliday junction (HJ) resolvases are structure-specific endonucleases that cleave four-way DNA junctions (HJs) generated during DNA recombination and repair. Bacterial RuvC, a prototypical HJ resolvase, functions as homodimer and nicks DNA strands precisely across the junction point. To gain insigh...

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Detalhes bibliográficos
Main Authors: Chen, Luan, Shi, Ke, Yin, Zhiqi, Aihara, Hideki
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3592405/
https://ncbi.nlm.nih.gov/pubmed/23118486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks1015
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